Movie S2.
Node of Ranvier when VAMP2 dependent exocytosis in astrocytes was reduced. A z-series through sections acquired by serial block face scanning electron microscopy of a node of Ranvier in the optic nerve from a mouse expressing the dnVAMP2 gene [(gfap)dnVAMP2]. Note the enlarged nodal gap. Accompanies SBSEM section shown in Fig. 2.
Regulation of myelin structure and conduction velocity by perinodal astrocytes
PNAS. 2018. 115:11832-11837 DOI: 10.1073/pnas.1811013115