Movie S2.

Node of Ranvier when VAMP2 dependent exocytosis in astrocytes was reduced. A z-series through sections acquired by serial block face scanning electron microscopy of a node of Ranvier in the optic nerve from a mouse expressing the dnVAMP2 gene [(gfap)dnVAMP2]. Note the enlarged nodal gap. Accompanies SBSEM section shown in Fig. 2.

Regulation of myelin structure and conduction velocity by perinodal astrocytes

Dipankar J. Dutta, Dong Ho Woo, Philip R. Lee, Sinisa Pajevic, Olena Bukalo, William C. Huffman, Hiroaki Wake, Peter J. Basser, Shahriar SheikhBahaei, Vanja Lazarevic, Jeffrey C. Smith, and R. Douglas Fields

PNAS. 2018. 115:11832-11837 DOI: 10.1073/pnas.1811013115