Locomotor impairment of Parl-/- mouse. Two seven week-old Parl-/- mice show the typical locomotor impairment, severe muscle atrophy, and dyspnea, at difference with an age matched WT littermate.
Marco Spinazzi, Enrico Radaelli, Katrien Horré, Amaia M. Arranz, Natalia V. Gounko, Patrizia Agostinis, Teresa Mendes Maia, Francis Impens, Vanessa Alexandra Morais, Guillermo Lopez-Lluch, Lutgarde Serneels, Placido Navas, and Bart De Strooper
PNAS. 2018. 116:277-286 DOI: 10.1073/pnas.1811938116