Animation showing changes in TCR occupation-probability density across a growing close contact over time. The probability of occupation is plotted on the z-axis, the ‘time’ given in the title is the time post initial contact, and the ‘remaining mass’ refers to the probability that the TCR is still found within the close contact. Close-contact growth rate is set to g = 0.1 μm2/s.
Ricardo A. Fernandes, Kristina A. Ganzinger, Justin C. Tzou, Peter Jönsson, Steven F. Lee, Matthieu Palayret, Ana Mafalda Santos, Alexander R. Carr, Aleks Ponjavic, Veronica T. Chang, Charlotte Macleod, B. Christoffer Lagerholm, Alan E. Lindsay, Omer Dushek, Andreas Tilevik, Simon J. Davis, and David Klenerman
PNAS. 2019. 116:14002-14010 DOI: 10.1073/pnas.1817255116