Sensory neurons wrap above the hair follicle bulge in young animal. Immunofluorescence of LRIG1 in white showing the hair follicle isthmus, and TUJ1 in red showing the sensory neurons targeting to the region below isthmus and above bulge in young skin. Five independent biological replicates were performed, shown are representative images.
Yejing Ge, Yuxuan Miao, Shiri Gur-Cohen, Nicholas Gomez, Hanseul Yang, Maria Nikolova, Lisa Polak, Yang Hu, Akanksha Verma, Olivier Elemento, James G. Krueger, and Elaine Fuchs
PNAS. 2020. 117:5339-5350 DOI: 10.1073/pnas.1901720117