Sensory neurons mis-target to the bulge in aged animal. Immunofluorescence of LRIG1 in white showing the hair follicle isthmus, and TUJ1 in red showing the sensory neurons mis-targeting to the bulge in aged skin. Five independent biological replicates were performed, shown are representative images.
Yejing Ge, Yuxuan Miao, Shiri Gur-Cohen, Nicholas Gomez, Hanseul Yang, Maria Nikolova, Lisa Polak, Yang Hu, Akanksha Verma, Olivier Elemento, James G. Krueger, and Elaine Fuchs
PNAS. 2020. 117:5339-5350 DOI: 10.1073/pnas.1901720117