Movie S1.

Focused ultrasound triggers repetitive emission of 470-nm light in an artificial circulatory system. This movie shows the repetitive emission of 470-nm light in the center of the tubing when excited by FUS, which is indicated by the red dot in the upper left corner of the frames. The intensity of 470-nm luminescence is indicated by a colormap ranging from dark blue through blue, cyan, green, yellow to red with increasing intensity. The frame rate is 25 frames per second (fps) and the video is played at real time. Detailed protocol for FUS-triggered mechanoluminescence of artificial circulation system to mimic blood circulation is described in Materials and Methods.