Movie S7.

hIAPP aggregation at the AWI - bIAPP with avidin D fluorescein in D₂O. hIAPP aggregates accumulate at the AWI, forming ‘clusters’ that become immobile. 3.6 µM hIAPP was incubated with 0.4 µM bIAPP-0.08 µM avidin D fluorescein in D₂O in a well of a 96-well plate. The well was imaged, z stacks encompassing the AWI and an area spanning 1417x1417 µm² were collected for at least 18 h. 3D projections were performed in Imaris and visualised with the AWI at the front facing the experimentalist and the bulk solution behind it.