Movie S1.
Time-lapse video of MCF10A cells and PTEN-/- cells in response to 5 μM pitavastatin. Pitavastatin was added at time 0, images were acquired every 10 min.
Statin-induced GGPP depletion blocks macropinocytosis and starves cells with oncogenic defects
PNAS. 2020. 117:4158-4168 DOI: 10.1073/pnas.1917938117