Movie S1.

Time-lapse confocal imaging of histone eviction upon treatment with Doxo, Amr or Etop. Cells were treated with the indicated drugs and histone eviction was followed for 1 hour after photoactivation of the indicated region by time lapse confocal microscopy. Related to Figure 2.

Uncoupling DNA damage from chromatin damage to detoxify doxorubicin

Xiaohang Qiao, Sabina Y. van der Zanden, Dennis P. A. Wander, Daniel M. Borràs, Ji-Ying Song, Xiaoyang Li, Suzanne van Duikeren, Noortje van Gils, Arjo Rutten, Tessa van Herwaarden, Olaf van Tellingen, Elisa Giacomelli, Milena Bellin, Valeria Orlova, Leon G. J. Tertoolen, Sophie Gerhardt, Jimmy J. Akkermans, Jeroen M. Bakker, Charlotte L. Zuur, Baoxu Pang, Anke M. Smits, Christine L. Mummery, Linda Smit, Ramon Arens, Junmin Li, Hermen S. Overkleeft, and Jacques Neefjes

PNAS. 2020. 117:15182-15192 DOI: 10.1073/pnas.1922072117

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