Movie S2.
Immunofluorescence analysis of LRCH1 (blue), LAT (green) and LAMP1 (red) colocalization. Multiple layers of the resting (Movie S1-0min) or anti-CD3/CD28-stimulated (Movie S2-30min) HA-LRCH1-transduced T8.1 cells were taken, and merged by the ZEN software.
LRCH1 deficiency enhances LAT signalosome formation and CD8+ T cell responses against tumors and pathogens
PNAS. 2020. 117:19388-19398 DOI: 10.1073/pnas.2000970117