Movie S1.

B. thailandensis infected multinucleated giant cell containing highly condensed mitotic-like chromosomes. Cell rounds up, initiates cytokinesis but eventually abort the process. HepG2 cells were infected with mApple fluorescent B. thailandensis (in Red) and stained with CellMask plasma membrane dye (in Magenta) and Hoechst 33342 DNA dye (in Blue).

Bacterial-induced cell fusion is a danger signal triggering cGAS–STING pathway via micronuclei formation

Joanne Wei Kay Ku, Yahua Chen, Bryan Jian Wei Lim, Stephan Gasser, Karen Carmelina Crasta, and Yunn-Hwen Gan

PNAS. 2020. 117:15923-15934 DOI: 10.1073/pnas.2006908117