Movie S5.

Three-dimensional rendering in Imaris of an in vivo fluorescent light-sheet micrograph from a 3dpi MTZ+ ablated Tg(mpeg1.1:Dendra2;rpe65a:nfsB-eGFP) larva. This is the same larva shown in Fig. 3B and B’ and SI Appendix, Movie S4. The original z-stack has been cropped (Fig. 3B; yellow box; crop dimensions=X:150μm, Y:200μm, Z:100μm; 1μm interval) to show morphology of MΦs/μglia labeled using the endogenous mpeg1.1:Dendra2 (red)+ signal (magenta). White labels endogenous eGFP+ signal (RPE). Anterior is up; scale bar represents 10μm. Definitions as follows: dpi, days post-injury; MTZ, metronidazole; RPE, retinal pigment epithelium.

The immune response is a critical regulator of zebrafish retinal pigment epithelium regeneration

Lyndsay L. Leach, Nicholas J. Hanovice, Stephanie M. George, Ana E. Gabriel, and Jeffrey M. Gross

PNAS. 2021. 118:None-None DOI: 10.1073/pnas.2017198118