Movie S1.

MD simulation of glycosylated EGFR (simulation 1). The Man3GlcNAc2 residues are colored in purple. EGFR ECD subdomains are color coded in blue (DI), green (DII), yellow (DIII), and red (DIV). The TMD is colored in orange, and the TKD in salmon. The movies were generated in VMD, and the trajectory smoothing window size was put to 20.