Movie S10.

Migration of GFP-centrin–expressing OT-I CD8+ T cells in Kb-Q4–coated microchannels. First line: green, centrin-GFP; red, Hoechst. Second line: MTOC (green) and nucleus (red) tracking. Third line: MTOC trajectory. Images were acquired every 35 s.

Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest

Hélène D. Moreau, Fabrice Lemaître, Kym R. Garrod, Zacarias Garcia, Ana-Maria Lennon-Duménil, and Philippe Bousso

PNAS. 2015. 112:12151-12156 DOI: 10.1073/pnas.1506654112