Movie S1.
Location of mimetic peptides in the folded B7-2 monomer. Colors correspond to those in Fig. 4B. In the B7-2 extracellular domain (1I85.pdb), blue-gray residues overlap between homodimer interface peptides pB2-4 (green) and pB2-7 (dark blue) and between pB2-7 and pB2-6 (red), respectively. Peptides outside the homodimer interface are pB2-2 (orange), pB2-3 (yellow), and pB2-5 (pink).
Superantigens hyperinduce inflammatory cytokines by enhancing the B7-2/CD28 costimulatory receptor interaction
PNAS. 2016. 113:E6437-E6446 DOI: 10.1073/pnas.1603321113