Movie S1.

Morphing movie illustrating the transition between the crystal structure of MALTIR and the solution structure of MALTIRC116A. The structures are shown in cartoon representation, with the side chains of C89, C134, and P125 highlighted in stick representation. The movie was generated using UCSF Chimera (1).

Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling

Mark M. Hughes, Peter Lavrencic, Rebecca C. Coll, Thomas Ve, Dylan G. Ryan, Niamh C. Williams, Deepthi Menon, Ashley Mansell, Philip G. Board, Mehdi Mobli, Bostjan Kobe, and Luke A. J. O’Neill

PNAS. 2017. 114:E6480-E6489 DOI: 10.1073/pnas.1701868114