Movie S3.

Homooligomerization of activated Cry2 is enhanced when concentrated on the surface of an organelle. Human fibroblast expressing CIBN-Mito and mCherry-Cry2. The Cry2/CIB1 system was activated by 488-nm laser pulses delivered to a 3-μm × 3-μm area (blue square), as indicated. The enrichment of activated Cry2 on the surface of an organelle (mitochondria in this case) dramatically facilitates homooligomerization of activated Cry2. (Scale bar: 3 μm.)