Movie S4.

Activated Cry2 homooligomerization on the surface of small organelles under whole-cell irradiation. Human fibroblast expressing CIBN-Mito and mCherry-Cry2. The Cry2/CIB1 system was activated throughout the cell by a single 488-nm laser pulse of 200 ms. Cry2 homooligomerization process only starts after accumulation of activated Cry2 on the surface of mitochondria. (Scale bar: 5 μm.)