Movie S3.

Flow velocity in the microfluidic chip and through the BoPV niche. Representative movie showing the engineered niches cultured in the perfusion chamber and exposed to unidirectional fluid flow (top view).

Human bone perivascular niche-on-a-chip for studying metastatic colonization

Alessandro Marturano-Kruik, Michele Maria Nava, Keith Yeager, Alan Chramiec, Luke Hao, Samuel Robinson, Edward Guo, Manuela Teresa Raimondi, and Gordana Vunjak-Novakovic

PNAS. 2018. 115:1256-1261 DOI: 10.1073/pnas.1714282115