Movie S7.
Breast cancer cells disseminated in the BoPV niche-on-chip exposed to interstitial flow. Video showing a live 3D confocal reconstruction of breast cancer cells (green; GFP-transduced MDA-MB-231) within the perivascular niches containing MSCs and RFP-expressing ECs (red) cultured under interstitial flow.
Human bone perivascular niche-on-a-chip for studying metastatic colonization
PNAS. 2018. 115:1256-1261 DOI: 10.1073/pnas.1714282115