To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie S3. Mechanosensitive EC cells release 5-HT in response to membrane displacement. A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release Constanza Alcaino, Kaitlyn R. Knutson, Anthony J. Treichel, Gulcan Yildiz, Peter R. Strege, David R. Linden, Joyce H. Li, Andrew B. Leiter, Joseph H. Szurszewski, Gianrico Farrugia, and Arthur Beyder PNAS. 2018. 115:E7632-E7641 DOI: 10.1073/pnas.1804938115 Download Original Video Browse All Videos »