Movie S2.
Typical 500-frame TIRF movie of a living, DIV3 cortical p75NTR KO neuron expressing S6-tagged p75NTR and labeled with CoA-Abberior635P (∼0.38 spots/μm2). A mask, drawn on movie maximum intensity projection, was applied to exclude surrounding astrocytes signals, and fluorophores adhered to the glass because of PDL coating. Scale bar, 5μm.
Fast-diffusing p75NTR monomers support apoptosis and growth cone collapse by neurotrophin ligands
PNAS. 2019. 116:21563-21572 DOI: 10.1073/pnas.1902790116