Movie S1.
Network evolution during the initial 50 seconds of the simulated association phases for trivalent receptor-ligand interactions in which twisted configurations are either allowed or hindered through alterations to the [Leff] values that drive these binding conformations (see also Fig. 3).
Mechanisms of noncanonical binding dynamics in multivalent protein–protein interactions
PNAS. 2019. 116:25659-25667 DOI: 10.1073/pnas.1902909116