Movie 15.

Migration of Piezo null cell under 0.5% agarose gel to which a 1600 Pa compressive load is applied. The cell forms both pseudopods and blebs, unlike its wild-type parent, which exclusively forms blebs under the same conditions. Taken by a laser scanning confocal microscope (Zeiss 780) at 2 frames per second about 8-10 minutes after the load is applied.

Pressure sensing through Piezo channels controls whether cells migrate with blebs or pseudopods

Nishit Srivastava, David Traynor, Matthieu Piel, Alexandre J. Kabla, and Robert R. Kay

PNAS. 2020. 117:2506-2512 DOI: 10.1073/pnas.1905730117