Movie S2.

Time lapse video of mitotane-induced cell death in the presence of the caspase-inhibitor zVAD-fmk. Note that SYTOX^TM green, demonstrating necrotic cell death, is positive upon caspase-inhibition, but no blebbing of the mitotane-treated cells is detected.

Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis

Alexia Belavgeni, Stefan R. Bornstein, Anne von Mässenhausen, Wulf Tonnus, Julian Stumpf, Claudia Meyer, Evelyn Othmar, Markus Latk, Waldemar Kanczkowski, Matthias Kroiss, Constanze Hantel, Christian Hugo, Martin Fassnacht, Christian G. Ziegler, Andrew V. Schally, Nils P. Krone, and Andreas Linkermann

PNAS. 2019. 116:22269-22274 DOI: 10.1073/pnas.1912700116

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