Movie S1.

3D plot showing alignment of the ALK3^bright+ clusters against a scRNAseq dataset of the whole pancreas, confirming the ducto-acinar transitional axis and suggesting potential association of the pro-ductal and endocrine compartments. 3D UMAP plot showing cellular distribution when the ALK3^bright+ dataset (n=3, 4,878 cells) is mapped against two combined islet datasets claimed to represent the whole pancreas (3,277 cells). Clustering of pancreatic subtypes reflects differential gene expression and was validated by visualizing gene expression in UMAP plots.