Movie S4.

Animation showing construction of the antiparallel model from a single Dsc2-Dsg2 heterodimer (red/blue). Colored molecules represent the simulated system, gray molecules are periodic images. Water and ions are shown as spheres. Membranes (gray) are not part of the simulation setup and were added to guide the eye.

Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography

Mateusz Sikora, Utz H. Ermel, Anna Seybold, Michael Kunz, Giulia Calloni, Julian Reitz, R. Martin Vabulas, Gerhard Hummer, and Achilleas S. Frangakis

PNAS. 2020. DOI: 10.1073/pnas.2004563117