Example of a 3D echocardiographic reconstruction of a patient with pulmonary hypertension (end-diastolic volume 200 ml, end-systolic volume 137 ml, ejection fraction 31 %) showing an enlarged right ventricle (green) with a flattened septum in diastole (mesh) and even more so in systole. Both the longitudinal and lateral function appear altered. Data was processed with dedicated software (4D RV-Function, TomTec Imaging Systems). View Video 2 at http://movie-usa.glencoesoftware.com/video/10.1530/ERP-14-0077/video-2.